i/o Beauti
i/o Beauti is an inside-out longevity supplement formulated to support two of the most critical pathways in how skin ages: autophagy (your cells' ability to renew and repair themselves) and the gut–skin axis (the connection between gut health and visible skin quality).
The result is skin that looks healthier because it is healthier, from the cell up.
What it does
Supports cellular renewal and regeneration
Strengthens skin structure and barrier function
Promotes gut microbiome balance — the foundation of clearer, more resilient skin
Supports mitochondrial function and cellular energy
Influences pathways linked to hair and skin vitality
The three actives that make it work
Yüth® Spermidine — A naturally occurring polyamine that activates autophagy, the body's cellular recycling process. Recent research from Auburn University shows it supports cell viability, keratin production, mitochondrial function, and the genes linked to skin and hair vitality.
CoreBiome® Tributyrin — A bioavailable precursor to butyrate, the key molecule in the gut–skin axis. Supports gut barrier integrity, microbiome balance, and inflammatory regulation — creating the internal environment for clearer skin.
MCT Oil — Rapidly absorbed medium-chain triglycerides that enhance the bioavailability of the formula and serve as clean fuel for cellular energy.
i/o Beauti is an inside-out longevity supplement formulated to support two of the most critical pathways in how skin ages: autophagy (your cells' ability to renew and repair themselves) and the gut–skin axis (the connection between gut health and visible skin quality).
The result is skin that looks healthier because it is healthier, from the cell up.
What it does
Supports cellular renewal and regeneration
Strengthens skin structure and barrier function
Promotes gut microbiome balance — the foundation of clearer, more resilient skin
Supports mitochondrial function and cellular energy
Influences pathways linked to hair and skin vitality
The three actives that make it work
Yüth® Spermidine — A naturally occurring polyamine that activates autophagy, the body's cellular recycling process. Recent research from Auburn University shows it supports cell viability, keratin production, mitochondrial function, and the genes linked to skin and hair vitality.
CoreBiome® Tributyrin — A bioavailable precursor to butyrate, the key molecule in the gut–skin axis. Supports gut barrier integrity, microbiome balance, and inflammatory regulation — creating the internal environment for clearer skin.
MCT Oil — Rapidly absorbed medium-chain triglycerides that enhance the bioavailability of the formula and serve as clean fuel for cellular energy.
Key Actives
Tributyrin (as CoreBiome®) – A patented tributyrin, which is a type of short-chain fatty acid that is produced by beneficial bacteria in the gut. It has been shown to improve gut health by nourishing the gut lining and supporting the growth of beneficial gut bacteria.
Taking i/o Beauti daily can help improve the balance of your gut microbiome, support the gut-skin axis, and improve overall gut health as well as the health of your hair, skin, and nails.
What is the gut-skin axis? Research has shown that there is a direct connection between the health of your gut and the appearance and health of your skin. Your gut is home to trillions of microorganisms, collectively known as the gut microbiome, which play a crucial role in maintaining your overall health, including your skin health.
Summary of benefits from our skin care and gut health supplement include:
- Helps support digestive, gut, and gastrointestinal health through impacting gene expression
- Helps support microbiome health by mediating microbe-to-host-immune-system cross-talk
- Supports immune health by promoting a healthy microbiome and by supporting tight junctures in the intestinal lining
- Promotes a healthy microbiome and balanced flora
- Helps support gut health (digestive health) and the gut-skin axis
- Supports intestinal walls
- Supports regularity (helps alleviate occasional constipation)
- Helps regulate the normal inflammatory response in the gastrointestinal tract
- Helps provide antioxidant protection and fights oxidative stress
Biogenic Polyamine (Yuth™) - i/o Beauti also contains a powerful ingredient called Yüth, a patented polyamine that supports healthy aging and promotes healthy skin, hair, and nails.
Polyamines are organic essential nutrients found in every cell of our body, including the cells that promote health in our skin, hair, and nails. They play a vital role in cell growth, repair, and maintenance and have been shown to have numerous health benefits for our body and skin.
Polyamines have potent anti-aging benefits through a process called Autophagy. This is your body's way of cleaning out damaged cells to regenerate newer, healthier cells. As we age, our body's ability to produce polyamines decreases, leading to cellular damage and visible signs of aging. Supplementing with polyamines through our gut health supplement can help support slow aging and beauty-from-within by promoting cellular repair and youthful cells.
Incorporating polyamines into your daily regimen also promotes healthy skin by supporting the production of collagen as well as helps to improve the strength and elasticity of your hair, making it less prone to breakage and damage.
Benefits of polyamines include:
- Supports and activates autophagy
- Supports collagen production
- Promotes cellular repair and youthful cells
- Supports healthy aging
- Supports mitochondrial health
- Supports DNA stability
- Helps support a normal inflammatory response
- Helps modulate oxidative stress
- Supports brain and cognitive health
Ingredients List
How to Use
The Skin Moderne Difference
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