The Science of Skin Longevity

Targeting the biological drivers of aging at the cellular level

Bio-Compatible Beauty

At Skin Moderne, we've redefined skincare by targeting the biological drivers of aging at the cellular level. Our formulations are built on cutting-edge biotechnology and consciously created bioactive ingredients that align with your body's natural biological and cell-signaling processes—promoting healthier, more radiant, youthful skin from within.

12 Hallmarks of Aging

Modern science has identified 12 biological hallmarks that drive the aging process. Skin Moderne targets these fundamental mechanisms at the cellular level.

Genomic Instability

DNA damage from environmental stress and replication errors

Telomere Attrition

Protective chromosome ends shorten with age

Epigenetic Alterations

Changes in gene expression patterns over time

Loss of Proteostasis

Buildup of damaged proteins in cells

Deregulated Nutrient Sensing

Metabolic pathway imbalances affect cell function

Mitochondrial Dysfunction

Declining energy and increased oxidative stress

Cellular Senescence

'Zombie cells' secrete inflammatory factors

Stem Cell Exhaustion

Decreased tissue regenerative capacity

Altered Cell Communication

Pro-aging changes in intercellular signaling

Chronic Inflammation

Persistent inflammation damages tissues over time

Disabled Macroautophagy

Impaired cellular waste recycling

Microbiome Dysbiosis

Gut imbalance affects immunity and skin health

Longevity Innovations

Targeting the biological drivers of skin aging with consciously created bioactive ingredients developed through proprietary biotechnology.

Exosomes Regenerative Complex

We harness the power of plant-derived exosomes—nature's intelligent bio-communicators—to support regenerative skin health. Our plant-derived exosomes offer exceptional biocompatibility and are naturally designed to enter human cells via endocytosis or membrane fusion, delivering potent bioactivity at the cellular level.

Rich in proteins, lipids, nucleic acids, antioxidants, microRNAs, and phytonutrients, they help regulate gene expression and optimize intercellular signaling, promoting healthier, more resilient skin.

Patented Purification Technology

Not all plant exosome technologies are created equal. Many systems suffer from low purity, poor yields, and structural damage due to filter clogging and inefficient processing.

Skin Moderne overcomes these limitations with our patented Electrophoretic Oscillation Assisted Tangential Flow Filtration (EpOTFF)—an advanced processing and purification method ensuring exceptional purity, integrity, potency, and higher yields.

We further enhance efficacy through our Membrane-Fusion-Based Hybridization Technology—a breakthrough innovation that allows us to produce hybrid exosomes, a first in the skincare industry.

269+ Billion Exosomes Per mL

Independent lab testing confirms the exceptional quality of our Exosomes Regenerative Complex—among the most concentrated on the market. Particle size distribution falls within the ideal 40–160 nm range, with rigorous multi-batch testing to verify integrity and reliability of every product we deliver.

Key Ingredients: Exosomes Complex

Brassica Oleracea & Cucumis Sativus Vesicles

This advanced exosome hybrid is rich in diverse bioactive compounds, offering a multifaceted approach to skin health. It supports the restoration and reinforcement of the skin barrier, enhances moisturization, stimulates ceramide and collagen synthesis, provides antioxidant defense, improves the integrity of the dermal-epidermal junction, promotes skin brightening, and offers soothing benefits while protecting against environmental stressors.

Niacinamide (Vitamin B3)

A high-performance, multitasking active that strengthens the skin barrier, reduces redness, minimizes pores, balances oil production, fades dark spots, boosts collagen, protects against environmental damage, and enhances the absorption and efficacy of other active ingredients.

Sodium Hyaluronate

A high-purity, highly bio-compatible form of hyaluronic acid that penetrates deeply to attract and retain moisture within the skin. It supports hydration, improves elasticity, reduces trans-epidermal water loss (TEWL), enhances skin barrier integrity, and boosts the delivery and performance of other active ingredients.

Cell-CPR: Cell Resuscitation Serum

A comprehensive cellular rejuvenation treatment designed to target the 12 hallmarks of aging. Featuring consciously created bioactive ingredients developed through proprietary biotechnology, with biohacking properties that align with the body's natural biological and cell-signaling processes.

These ingredients work in synergy to enhance cell-to-cell communication, promoting skin firming, tightening, brightening, overall skin wellness, for healthier, more radiant, youthful skin.

Cell-CPR Benefits

Boosts Autophagy

Promotes elimination of senescent 'zombie cells'

Energizes Mitochondria

Increases cell longevity and energy production

DNA + Epigenetic Defense

Shields genetic integrity and counters aging-induced epigenetic changes

Firms + Brightens

Boosts collagen and elastin for firmer, brighter, hydrated skin

Key Ingredients: Cell-CPR

Heptasodium Hexacarboxymethyl Dipeptide-12

A patented peptide that activates autophagy with additional anti-aging, anti-inflammatory, antioxidant, skin moisture retention, and hydration properties. It also enhances the skin barrier function.

Hexapeptide-2

Delivers powerful anti-aging benefits that effectively reduce wrinkles through stimulation of cell-to-cell communication in the keratinocyte cells (Epidermis), collagen production in the fibroblast cells (Dermis), and adipogenesis in the pre-adipocyte cells (Hypodermis).

Benzoyl Tryptamine — Senescence Detoxifier

An indoleamine metabolite with 'dermohacker' properties that triggers the removal of harmful senescent cells while promoting healthy, youthful cells. Instead of dying like normal aged cells, senescent cells become 'zombie cells'—spewing inflammatory compounds linked to age-related conditions.

Helianthus Annuus (Sunflower) Sprout Extract

Boosts NAD+ levels, counteracts aging-induced epigenetic alterations, suppresses the formation of senescent cells, and improves cellular metabolism.

Proprietary Hybrid Exosomes

Citrus Paradisi Fruit Vesicles combined with Brassica Oleracea & Cucumis Sativus Vesicles—proprietary hybrid exosomes with potent anti-aging properties from boosting fibroblasts, to brightening skin, to repairing DNA.

i/o Beauti — Beauty Starts From Within

Skin Moderne has redefined beauty from the inside out with i/o Beauti—the first supplement designed to target both skin health and the gut microbiome.

Research shows a direct link between gut health and skin appearance. The trillions of microorganisms in your gut microbiome influence everything from digestion to immunity—and play a vital role in maintaining clear, radiant, and resilient skin.

Key Ingredients: i/o Beauti

Tributyrin (CoreBiome®)

A patented form of tributyrin, a naturally occurring ester of butyric acid (a short-chain fatty acid found in certain foods and produced by beneficial gut bacteria). CoreBiome® nourishes the gut lining, reduces inflammation, and supports the growth of beneficial microbes for improved gut health.

Spermidine (Yüth™)

A patented polyamine that supports healthy aging while promoting vibrant skin, hair, and nails. Polyamines play a powerful role in anti-aging through autophagy—the body's natural process of clearing damaged cells and regenerating healthier ones. As we age, polyamine levels decline, leading to cellular damage and visible signs of aging. Supplementing with polyamines helps restore this process, boosting collagen production for smoother, firmer skin.

Professional Treatment Devices

Two technologies. One outcome. Next-level longevity. Unmatched results.

Powerful on their own. Transformative together—delivering elevated, accelerated results. Portable. Precise. Powerfully regenerative.

NanoFusion®

An unparalleled multi-action skin treatment device that infuses active ingredients into the skin four times more effectively than classic transdermal methods.

It amplifies skin rejuvenation, oxygenates, plumps, and smooths—all without injuring the skin. Safe, painless, legal for estheticians to use in every state, clinically proven and protected by patents.

UltraFusion®

An exceptionally designed skin treatment that transmits powerful and precise 10MHz ultrasound waves that stimulate cell regeneration, tissue improvement, enhance elasticity, firmness, and hydration—all without doing harm.

Safe, painless, legal for estheticians to use in every state, clinically proven and protected by patents.

Our Commitment to Quality

High Purity

Patented filtration ensures maximum potency

Clinical Strength

Professional-grade biotechnology formulations

Bio-Compatible

Works with your body's natural processes

Clean + Ethical

Plant-derived, vegan, non-toxic, and cruelty-free

Richard Purvis

Founder & CEO
Notable health and wellness practitioner and author of Recalibrate: Six Secrets to Resetting Your Age, Richard Purvis has more than 30 years of dedicated experience in nutrition, exercise, anti-aging, and overall wellness.

Purvis is the founder and innovator of numerous wellness brands, including Skin Moderne, Elementals, Live, Skin Moderne Professional Beauty, multi-patented beauty devices NanoFusion and UltraFusion, Cell-CPR, and i/o Beauti.

Dr. Frank Roesken

MD, PhD — Medical Advisor
With a dual background in wound healing and aesthetic dermatology, Dr. Roesken has spent his career bridging the gap between clinical science and personalized care. He is the co-founder of NanoFusion, CEO of THERAPEIA Cosmetics, and Medical Advisor at Skin Moderne.

Dr. Roesken attended University of Munich and Tulane Medical School in New Orleans and served as a specialist and senior consultant of Plastic Surgery at German university hospitals. He is the author of more than 100 scientific papers and a well-known speaker at international congresses.

Under his guidance, Skin Moderne has pioneered a patented purification process for plant-derived exosomes, ensuring maximum purity, integrity, and potency for next-generation skincare ingredients. As featured in Dermatology Times, Dr. Roesken leads Skin Moderne's commitment to science-backed, biocompatible skincare that supports cell proliferation, reduces inflammation, strengthens the skin barrier, and promotes cellular communication.

Dorie Collins

National Sales Director
Dorie has more than 20 years experience in the professional esthetic beauty industry. She has been a top skincare business development manager, receiving numerous awards for top sales in her territories; a product and brand manager; an esthetic treatment educator; and she is a licensed esthetician. Dorie is also a graduate of Brooks College.

Dorie's sales and brand/product development successes have always centered around education, for which she is passionate about. She believes that for her clients to fully succeed they must understand everything about the products and treatments they are administering and selling. This includes full conception of ingredient functions and efficacies, correct application, and protocol adherence, all to ensure the best possible results for her clients and in turn, their clients.

Bio-Compatible Beauty. Science-Driven Results.

Experience the future of intelligent, bio-compatible skin regeneration.