i/o Beauti

15 reviews
$39.95

A longevity supplement that works skin from the inside out. Unlike traditional collagen supplements, i/o Beauti supports autophagy - your body's natural cellular renewal process - helping skin cells clear out damaged components and recycle them to function more efficiently, supporting healthier, more resilient skin over time.

Because your skin doesn't exist in isolation.


Primary Benefit Gut-Skin Support
Also Supports Anti-Oxidant
Good For
autophagygut healthgut-skin
Supplement Capsule
Quantity
10% OFF Applied at Checkout
$39.95
Size: 30 capsules
$39.95 Extra 10% Off — Applies at Checkout!
Free shipping on orders $100+
Ships within 1-2 business days
30-day satisfaction guarantee
Loved for a Reason
5.0

I've had such a great experience with Skin Moderne. I really appreciate their science-driven approach to skin health and wellness. The products are beautifully formulated, effective, and feel luxurious. I especially love the Cell CPR, i/O Beauti, and the serums, all have become favorites. Highly recommend.

Suzanna Verified Review
Recommended Use

How to Use

Take one capsule per day in the AM on empty stomach
Key Actives

CoreBiome® Tributyrin
A patented form of tributyrin, a beneficial short-chain fatty acid naturally produced by the gut microbiome. It helps nourish the gut lining and support beneficial gut bacteria, strengthening the gut-skin axis - the connection between gut health and the appearance of your skin. With trillions of microorganisms influencing your overall health, a balanced gut microbiome plays an important role in supporting healthier-looking skin.

Key Benefits

  • Supports gut and digestive health
  • Helps maintain a healthy gut microbiome
  • Strengthens the gut-skin axis
  • Supports immune health
  • Supports a normal inflammatory response
  • Provides antioxidant protection

Yüth™ Biogenic Polyamine
A patented polyamine with powerful anti-ageing benefits that supports autophagy - your body's natural cellular renewal process. As natural polyamine levels decline with age, Yüth™ helps support cellular repair, collagen production and healthier skin, hair and nails, promoting skin longevity from within.

Key Benefits

  • Supports autophagy
  • Supports collagen production
  • Promotes cellular repair
  • Supports healthy ageing
  • Supports mitochondrial health
  • Supports DNA stability
  • Supports a normal inflammatory response
  • Helps modulate oxidative stress
Ingredients List
Tributyrin (as CoreBiome®),  Biogenic Polyamine (Yuth™), Vitamin A (Retinyl Palmitate), Vitamin D3 (Cholecalciferol), Vitamin E (d-Alpha Tocopherol), Biotin, Vegetable Capsule (Hypromellose), & MCT (Medium Chain Triglycerides) Oil.
Advanced Technology
Autophagy ActivationActivates cellular cleanup and renewal processes
Clinical Strength
Non-Toxic
High Purity
Vegan
Bio-Compatible
i/o Beauti
$39.95

SKIN MODERNE HAS BEEN FEATURED ON

i/o Beauti

Built Different

Not Your Average Skincare

Most skincare starts with active ingredients. We start with patented technologies that help those ingredients perform at their full potential - from advanced delivery systems to proprietary stabilisation methods developed to maximise results.

Cellular, Not Cosmetic

Healthy skin starts at the cellular level. That's why our formulas are designed to support the biological processes behind healthier, stronger and more resilient skin, rather than simply masking visible concerns.

Purpose Over Popularity

Every ingredient has earned its place. We don't formulate around trends or unnecessary fillers - only technologies and ingredients selected because they make a meaningful difference to your skin.

What To Expect

Month 1: Foundation building
  • Inside: Nourishing the gut lining, activating autophagy
  • Outside: Digestion feels settled, skin comfort improving
Month 2: Renewal underway
  • Inside: Accelerating cellular repair, calming inflammation
  • Outside: Less redness and reactivity, subtle glow emerging
Month 3: Visible shift
  • Inside: Supporting collagen synthesis, strengthening gut-skin axis
  • Outside: Skin clearer, tone more even, texture smoother and firmer
Month 4+: Transformed within
  • Inside: Autophagy sustained and ongoing, cellular aging decelerating
  • Outside: Fine lines softer, tone unified, hair and nails visibly stronger

Complete Your Routine

Curated pairings to build your perfect regimen.

Cell-CPR Eye

Cell-CPR Eye

$75.00
View product
Cell-CPR Face

Cell-CPR Face

$95.00
View product
EXOSOMES REGENERATIVE COMPLEX

EXOSOMES REGENERATIVE COMPLEX

$255.00
View product

Trusted by Skincare Professionals At

Trusted Worldwide

20,000+ Skincare Professionals Nationwide
200,000+ Customers Worldwide

Real Skin. Real Results.

See why thousands trust Skin Moderne every day.

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Results Worth Talking About

Cell Renewal + Communication Peptides
Cellular Energy + Longevity Boosters
Exosome + Vesicle Technology
Senescence + Cellular Detoxifiers
Hydration + Volume Technology