The Future of Skin Health Starts Within

True skin transformation doesn’t begin at the surface—it starts at the cellular level.

I/O Beauti is an advanced, inside-out longevity formula designed to support the biological processes that drive skin health, regeneration, and resilience—working through two of the most critical pathways in aging: autophagy and the gut–skin axis.

Recent efficacy results from Auburn University, published late last year, using our core raw material Yüth® (biogenic polyamine spermidine), have demonstrated highly promising outcomes.

·      Increased cell viability

·      Enhanced keratin protein production, essential for skin structure and barrier function

·      Upregulation of genes linked to hair follicle formation

·      Support mitochondrial function (critical for cellular energy regulation)

·      Influence gene expression related to cell growth and metabolism, suggesting broader benefits for overall cellular homeostasis

 Collectively, these findings indicate that spermidine may help support skin health, regeneration, and potentially hair growth.

Powered by Three Synergistic Components

1.    Yüth® (Spermidine)

A cellular renewal activator

Spermidine is a naturally occurring polyamine known for its ability to support autophagy - the body’s essential cellular recycling and repair process.

Emerging research, including findings from Auburn University, shows spermidine supports:

·      Cellular renewal and regeneration

·      Keratin production for stronger skin structure and barrier function

·      Hair follicle–related gene signaling

·      Mitochondrial function and cellular energy

2. CoreBiome® (Tributyrin)

A gut–skin axis optimizer

CoreBiome® delivers tributyrin, a highly bioavailable precursor to butyrate—a key molecule in the gut–skin axis.

CoreBiome® supports:

·      Gut barrier integrity and microbiome balance

·      Immune and inflammatory regulation

·      Cellular energy metabolism

By improving gut health, it helps create the internal environment for clearer, stronger, more resilient skin.

3. MCT Oil (Medium-Chain Triglycerides)

A rapid absorption and delivery enhancer

MCT oil serves as both a functional carrier and a metabolic support ingredient within the formula.

Unlike long-chain fats, MCTs are:

·      Rapidly absorbed and utilized by the body

·      Efficiently transported to the liver for quick energy production

In I/O Beauti, MCT oil helps:

·      Enhance bioavailability of lipid-soluble compounds

·      Support efficient transport of actives through the digestive system

·      Provide a clean, readily available energy source for cellular function

This makes it a critical component in optimizing how the formula is delivered and utilized.

Advanced Delivery for Maximum Bioavailability

I/O Beauti utilizes a multi-phase delivery system designed to:

·      Harmonize water- and lipid-soluble ingredients

·      Protect sensitive actives through digestion

·      Deliver nutrients where absorption is highest

The result is greater stability, enhanced absorption, and consistent performance.

Why Inside-Out Longevity Matters

Skin aging is driven by internal biological processes—not just external factors.

I/O Beauti targets key longevity pathways, including:

·      Autophagy (cellular renewal and repair)

·      Gut–skin axis (inflammation and microbiome balance)

·      Mitochondrial function (cellular energy)

·      Structural protein support

Helping to improve:

·      Skin quality and resilience

·      Hydration and elasticity

·      Hair vitality

·      Overall cellular health

A Cleaner, More Targeted Formula

·      With advancements in encapsulation technology, I/O Beauti has evolved:

·      No Vitamin A (more inclusive, including for pregnancy considerations)

·      Optimized stability without unnecessary additives

·      Focused, bio-compatible formulation

You may notice the capsules are now clear rather than golden—this reflects a cleaner formulation, not a change in efficacy.

The Skin Moderne Standard

Science-driven. Bio-compatible. No compromises.

I/O Beauti represents a new category of beauty—longevity-driven, inside-out skin health.